BioTissue Surgical was born of a life-changing need to deliver optimal patient healing outcomes. With over three decades of continual advancements in regenerative medcine, Bio Tissue Surgical, previously Known as Amniox Medical, is a pioneer in the clinical application of human birth tissue allografts to aid in the treatment of wounds, musculoskeletal conditions, and trauma-induced injuries.

Where Science Meets Nature

For over 36 years, our pioneering scientists have focused on understanding the regenerative features of human birth tissue—ultimately identifying HC-HA/PTX3 as a key orchestrator in human birth tissue regenerative healing. BioTissue Surgical allografts are aseptically processed, devascularized, and cell devitalized.

Learn more about our Proprietary Technology




Biological Tissue Provides the Most Human Form of Healing

Harness the Power of Human Birth Tissue

Developed by pioneers in the field of regenerative medicine, Clarix cryopreserved allograft derived from the umbilical cord that is used as a surgical covering to facilitate the healing process across a range of surgical specialties.9-16



Advanced Wound Therapy. Beyond Compare.

With the umbilical cord as its primary platform, the Neox family of products is used as a wound covering to manage chronic and complex wounds. As an adjunct to standard therapy, the Neox family of allografts helps expedite healing with fewer applications while reducing the cost of care.3-8



The Physician Portal includes a variety of valuable educational resources to help you become more comfortable with our game-changing products so you can readily apply them in your clinical practice.

Learn more about our advanced platform technology and how it’s utilized in the most complex medical conditions, as well as the vast body of scientific and clinical research which backs its use.

What you’ll find in the Physician Portal:

  • Indications for several conditions and procedures
  • Implementation support and application guides
  • Peer-reviewed studies and abstracts on several topics and sub-specialties
  • Product inserts detailing product use

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7300 Corporate Center Drive, Suite 700, Miami, FL 33126


1. Cooke M, Tan EK, Mandrycky C, He H, O’Connell J, Tseng SC. Comparison of cryopreserved amniotic membrane and umbilical cord tissue with dehydrated amniotic membrane/chorion tissue. J Wound Care. 2014;23(10):465-476.
2. Tan EK, Cooke M, Mandrycky C, et al. Structural and biological comparison of cryopreserved and fresh amniotic membrane tissues. J Biomaterial T Eng. 2014;4:379-388.
3. Caputo WJ, Vaquero C, Monterosa A, et al. Wound Repair Regen. 2016;24(5):885-893.
4. Couture M. Wounds. 2016;28(7):217-25.
5. Margolis DJ, Allen-Taylor L, Hoffstad O, Berlin JA. Diabetes Care. 2002;25:1835–9.
6. Fife CE, Eckert KA, Carter MJ. Adv Wound Care. 2018;7:77–94.
7. Raphael A. J Wound Care. 2016;25(Sup7):S10-17.
8. Raphael A, Gonzales J. J Wound Care. 2017;26(Sup10):S38-44.
9. Tseng SC. Invest Ophthalmol Vis Sci. 2016;57(5):ORSFh1-ORSFh8.
10. Bemenderfer TB, Anderson RB, Odum SM, Davis WH. J Foot Ankle Surg. 2019;58(1):97-102.
11. DeMill SL, Granata JD, Berlet GC, et al. Surg Technol Int. 2014;25:257-61.
12. Ellington J, Ferguson C. Surg Technol Int. 2014;25:63–67.
13. Stewart CM. SunKrist J Trauma Emerg Med Acute Care. 2019;1(1):1-6.
14. Swan J. Surg Technol Int. 2014;25:73-78.
15. Warner M, Lasyone L. Surg Technol Int. 2014;25:251-5.
16. Papanna R, Moise KJ Jr, Mann LK, et al. Ultrasound Obstet Gynecol. 2016;47(2):168-76.

BioTissue Surgical products are authorized under the regulations of the Food and Drug Administration (FDA) governing the manufacture and sale of Human Tissue Products. They are sold as structural tissue product for homologous use and are used by physicians as barriers, wound coverings, conduits, and cushions in the treatment of their patients.